Phenyl N-(5,6-dimethyl-2-methoxypyridin-3-yl)carbamate → 1-[(5,6-Dimethyl-2-methoxypyridin-3-yl)aminocarbonyl]-4-(2,3,5,6-tetramethylphenyl)piperazine

HRID 377820Notes

Reaction equation

HRID 377820 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([NH:11][C:12](=[O:20])OC2C=CC=CC=2)[C:5]([O:9][CH3:10])=[N:6][C:7]=1[CH3:8].[CH3:21][C:22]1[C:27]([CH3:28])=[CH:26][C:25]([CH3:29])=[C:24]([CH3:30])[C:23]=1[N:31]1[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]1>>[CH3:1][C:2]1[CH:3]=[C:4]([NH:11][C:12]([N:34]2[CH2:35][CH2:36][N:31]([C:23]3[C:24]([CH3:30])=[C:25]([CH3:29])[CH:26]=[C:27]([CH3:28])[C:22]=3[CH3:21])[CH2:32][CH2:33]2)=[O:20])[C:5]([O:9][CH3:10])=[N:6][C:7]=1[CH3:8]

Participants

3

Reactant 2

HCID 11086894Phenyl N-(5,6-dimethyl-2-methoxypyridin-3-yl)carbamateHCID 234461571-(2,3,5,6-Tetramethylphenyl)piperazine

Product 1

HCID 193571891-[(5,6-Dimethyl-2-methoxypyridin-3-yl)aminocarbonyl]-4-(2,3,5,6-tetramethylphenyl)piperazineYield 71%

Procedure

Phenyl N-(5,6-dimethyl-2-methoxypyridin-3-yl)carbamate and 1-(2,3,5,6-tetramethylphenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Sources & evidence

ORD record
ord-3ff28dbb4b834fff91bb7ba1f9b76368
Source dataset
uspto-grants-2000_02
Patent number
US06028195

Reaction notes

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