Phenyl N-(5-ethyl-2-methoxy-6-methylpyridin-3-yl)carbamate → 1-[(5-Ethyl-2-methoxy-6-methylpyridin-3-yl)aminocarbonyl]-4-(3-thiophenyl)piperazine

HRID 377824Notes

Reaction equation

HRID 377824 reaction equation
[CH2:1]([C:3]1[CH:4]=[C:5]([NH:12][C:13](=[O:21])OC2C=CC=CC=2)[C:6]([O:10][CH3:11])=[N:7][C:8]=1[CH3:9])[CH3:2].[S:22]1[CH:26]=[CH:25][C:24]([N:27]2[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)=[CH:23]1>>[CH2:1]([C:3]1[CH:4]=[C:5]([NH:12][C:13]([N:30]2[CH2:31][CH2:32][N:27]([C:24]3[CH:25]=[CH:26][S:22][CH:23]=3)[CH2:28][CH2:29]2)=[O:21])[C:6]([O:10][CH3:11])=[N:7][C:8]=1[CH3:9])[CH3:2]

Participants

3

Reactant 2

HCID 19357010Phenyl N-(5-ethyl-2-methoxy-6-methylpyridin-3-yl)carbamateHCID 193570831-(3-Thienyl)piperazine

Product 1

HCID 193570701-[(5-Ethyl-2-methoxy-6-methylpyridin-3-yl)aminocarbonyl]-4-(3-thiophenyl)piperazineYield 63%

Procedure

Phenyl N-(5-ethyl-2-methoxy-6-methylpyridin-3-yl)carbamate and 1-(3-thiophenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Sources & evidence

ORD record
ord-4d05f1946ab64c0f8c539123c9b84009
Source dataset
uspto-grants-2000_02
Patent number
US06028195

Reaction notes

Loading…