1-(3-Hydroxyphenyl)piperazine → HCID 19357170, compound

HRID 377831Notes

Reaction equation

HRID 377831 reaction equation
[CH2:1]([C:3]1[N:8]=[C:7]([O:9][CH3:10])[C:6]([NH:11][C:12](=[O:20])OC2C=CC=CC=2)=[CH:5][C:4]=1[CH3:21])[CH3:2].[OH:22][C:23]1[CH:24]=[C:25]([N:29]2[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]2)[CH:26]=[CH:27][CH:28]=1>>[CH2:1]([C:3]1[N:8]=[C:7]([O:9][CH3:10])[C:6]([NH:11][C:12]([N:32]2[CH2:31][CH2:30][N:29]([C:25]3[CH:26]=[CH:27][CH:28]=[C:23]([OH:22])[CH:24]=3)[CH2:34][CH2:33]2)=[O:20])=[CH:5][C:4]=1[CH3:21])[CH3:2]

Participants

3

Reactant 2

HCID 27365971-(3-Hydroxyphenyl)piperazineHCID 19357011HCID 19357011, compound

Product 1

HCID 19357170HCID 19357170, compoundYield 56%

Procedure

Phenyl N-(6-ethyl-2-methoxy-5-methylpyridin-3-yl)carbamate and 1-(3-hydroxyphenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Sources & evidence

ORD record
ord-51df3e2be40d4c9fb994e079fa7daa25
Source dataset
uspto-grants-2000_02
Patent number
US06028195

Reaction notes

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