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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 377840Generated: October 30, 2026

1-(3,5-Difluorophenyl)piperazine → 1-[(5,6-Dimethyl-2-methoxypyridin-3-yl)aminothiocarbonyl]-4-(3,5-difluorophenyl)piperazine

https://huagongshe.com/reaction/377840

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3,5-Difluorophenyl)piperazineHCID 10987219—
ReactantPhenyl N-(5,6-dimethyl-2-methoxypyridin-3-yl)thiocarbamateHCID 53824458—
Product1-[(5,6-Dimethyl-2-methoxypyridin-3-yl)aminothiocarbonyl]-4-(3,5-difluorophenyl)piperazineHCID 5395630047%

Reaction Steps

Phenyl N-(5,6-dimethyl-2-methoxypyridin-3-yl)thiocarbamate and 1-(3,5-difluorophenyl)piperazine were reacted by the same way with the example 22 to obtain the titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06028195
Source datasetuspto-grants-2000_02
ORD IDord-5e7a8db62e54499bbb76cd56a4d72575
Source noteuspto-grants-2000_02