1-(3-Hydroxyphenyl)piperazine → HCID 54505116, compound

HRID 377845Notes

Reaction equation

HRID 377845 reaction equation
[CH3:1][O:2][C:3]1[C:8]([NH:9][C:10](=[S:18])OC2C=CC=CC=2)=[CH:7][C:6]([CH3:19])=[C:5]([CH2:20][CH2:21][CH3:22])[N:4]=1.[OH:23][C:24]1[CH:25]=[C:26]([N:30]2[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]2)[CH:27]=[CH:28][CH:29]=1>>[CH3:1][O:2][C:3]1[C:8]([NH:9][C:10]([N:33]2[CH2:32][CH2:31][N:30]([C:26]3[CH:27]=[CH:28][CH:29]=[C:24]([OH:23])[CH:25]=3)[CH2:35][CH2:34]2)=[S:18])=[CH:7][C:6]([CH3:19])=[C:5]([CH2:20][CH2:21][CH3:22])[N:4]=1

Participants

3

Reactant 2

HCID 27365971-(3-Hydroxyphenyl)piperazineHCID 53900517HCID 53900517, compound

Product 1

HCID 54505116HCID 54505116, compoundYield 48%

Procedure

Phenyl N-(2-methoxy-5-methyl-6-propylpyridin-3-yl)thiocarbamate and 1-(3-hydroxyphenyl)piperazine were reacted by the same way with the example 22 to obtain the titled compound.

Sources & evidence

ORD record
ord-28e547f0ebfa4422bcd9509845016e81
Source dataset
uspto-grants-2000_02
Patent number
US06028195

Reaction notes

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