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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 377856Generated: October 25, 2026

1-(3,5-Difluorophenyl)piperazine → 1-[(5-Acetyl-2-methoxy-6-methylpyridin-3-yl)aminocarbonyl]-4-(3,5-difluorophenyl)piperazine

https://huagongshe.com/reaction/377856

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3,5-Difluorophenyl)piperazineHCID 10987219—
ReactantPhenyl N-(5-acetyl-2-methoxy-6-methylpyridin-3-yl)carbamateHCID 19357047—
Product1-[(5-Acetyl-2-methoxy-6-methylpyridin-3-yl)aminocarbonyl]-4-(3,5-difluorophenyl)piperazineHCID 1935717577%

Reaction Steps

Phenyl N-(5-acetyl-2-methoxy-6-methylpyridin-3-yl)carbamate and 1-(3,5-difluorophenyl)piperazine were reacted by the same way with the example 46 to obtain the titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06028195
Source datasetuspto-grants-2000_02
ORD IDord-7af50b0a51d14ffa9ebff5f82d806c1c
Source noteuspto-grants-2000_02