Sodium borohydride → HCID 19357063, compound

Participants

Reaction Steps

1-[(5-Acetyl-2-methoxy-6-methylpyridin-3-yl)aminocarbonyl]-4-(3,5-dimethoxyphenyl)piperazine(100 mg, 0.23 mmol) was dissolved in anhydrous ethanol(15 ml) and NaBH4 (8.66 mg) was added. The reaction solution was stirred at room temperature for 2 hours. The mixture was concentrated under the reduced pressure to remove ethanol and purified by column chromatography (ethylacetate:hexane=2:1) to obtain the titled compound.

Provenance & Evidence