1-(2-Fluorophenyl)piperazine → HCID 19357126, compound

HRID 377872Notes

Reaction equation

HRID 377872 reaction equation
[CH3:1][O:2][C:3]1[C:12]([NH:13][C:14](=[O:22])OC2C=CC=CC=2)=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1.[F:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1[N:30]1[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]1>>[CH3:1][O:2][C:3]1[C:12]([NH:13][C:14]([N:33]2[CH2:32][CH2:31][N:30]([C:25]3[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=3[F:23])[CH2:35][CH2:34]2)=[O:22])=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1

Participants

3

Reactant 2

HCID 705291-(2-Fluorophenyl)piperazineHCID 19356985Phenyl N-(2-methoxyquinolin-3-yl)carbamate

Product 1

HCID 19357126HCID 19357126, compoundYield 81%

Procedure

Phenyl N-(2-methoxyquinolin-3-yl)carbamate and 1-(2-fluorophenyl)piperazine were reacted by the same way with the example 81 to obtain the titled compound.

Sources & evidence

ORD record
ord-9369d9a73cc04722b72e7cf3187b8db5
Source dataset
uspto-grants-2000_02
Patent number
US06028195

Reaction notes

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