HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → 2-Methoxy-4,5-dimethylaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 1-Methoxy-4,5-dimethyl-2-nitrobenzene | HCID 19357165 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Methoxy-4,5-dimethylaniline | HCID 19357140 | 82% |
Reaction Steps
Tetrahydrofuran(100 ml) and ethanol(40 ml) were added into 4,5-dimethyl-2-nitroanisole(7.80 g, 0.043 mol) and then added 10% Pd/activated carbon(0.57 g) slowly, hydrogenated for 5 hrs. The reaction was completed by the same way with the above and the resulting product was purified by column chromatography to obtain the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06028195 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-4c9f20c9fc284dd990bb3a0f2b887d33 |
| Source note | uspto-grants-2000_02 |