HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → 2-Amino-4,5-dimethylphenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 4,5-Dimethyl-2-nitrophenol | HCID 349117 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-4,5-dimethylphenol | HCID 81099 | 77% |
Reaction Steps
To 4,5-dimethyl-2-nitrophenol(11.7 g, 0.07 mol), tetrahydrofuran(100 ml) and ethanol(40 ml) were added, and 10% palladium/activated carbon(0.57 g) was added slowly, and then the mixture was hydrogenated for 5 hours. The reaction mixture was concentrated and chromatographed by the same way above to obtain the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06028195 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-3f2a1a0f09fe486b9818395566adab45 |
| Source note | uspto-grants-2000_02 |