HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,8-Diazabicyclo(5.4.0)undec-7-ene → HCID 19357171, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | 1-(3,5-Dimethoxyphenyl)piperazine | HCID 2736205 | — |
| Reactant | HCID 19357141 | HCID 19357141 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 19357171 | HCID 19357171 | 87% |
Reaction Steps
Phenyl N-[2-(t-butyldimethylsilyloxy)-4,5-dimethylphenyl]carbamate (0.17 g, 0.5 mmole) and 1-(3,5-dimethoxyphenyl)piperazine(0.13 g, 0.6 mmole) were dissolved in tetrahydrofuran(10 ml), and thereto with stirring DBU(0.09 g, 0.6 mmole) was added, and the resulting mixture was stirred for 2 hours, concentrated and chromatographed to obtain the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06028195 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-43f7544a2f264a4889248983421c8f43 |
| Source note | uspto-grants-2000_02 |