HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → N,N-diethyl 2-chloro-6-methylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 2-Chloro-N,N-diethylbenzamide | HCID 82566 | — |
| Product | N,N-diethyl 2-chloro-6-methylbenzamide | HCID 18630133 | 92% |
Reaction Steps
The compound from example e (1.0 eq) and MeI (3.0 eq) were combined according to Method A. The crude product was purified by HPLC with 1:4 EtOAc/hexanes to give 5.2 g of N,N-diethyl 2-chloro-6-methylbenzamide as a yellow solid, a 92% yield. m.p. 48°-49° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06028101 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-00d9f08a6eeb4b4fa197cc1dd4376aab |
| Source note | uspto-grants-2000_02 |