HCID 178472108, compound → HCID 178473543, compound

HRID 378153Notes

Reaction equation

HRID 378153 reaction equation
NC(NC1C=C(C(NCC(NC(C2C=C(Cl)C=C(Cl)C=2)CC(OCC)=O)=O)=O)C=CC=1)=NC#N.[Cl:35][C:36]1[CH:37]=[C:38]([CH:43]([NH:52][C:53](=[O:78])[CH2:54][NH:55][C:56]([C:58]2[CH:63]=[CH:62][CH:61]=[C:60]([NH:64][C:65]([NH:72][C:73]([O:75][CH2:76][CH3:77])=[O:74])=[N:66][C:67]([O:69][CH2:70][CH3:71])=[O:68])[CH:59]=2)=[O:57])[CH2:44][C:45]([O:47]C(C)(C)C)=[O:46])[CH:39]=[C:40]([Cl:42])[CH:41]=1>>[Cl:35][C:36]1[CH:37]=[C:38]([CH:43]([NH:52][C:53](=[O:78])[CH2:54][NH:55][C:56]([C:58]2[CH:63]=[CH:62][CH:61]=[C:60]([NH:64][C:65]([NH:72][C:73]([O:75][CH2:76][CH3:77])=[O:74])=[N:66][C:67]([O:69][CH2:70][CH3:71])=[O:68])[CH:59]=2)=[O:57])[CH2:44][C:45]([OH:47])=[O:46])[CH:39]=[C:40]([Cl:42])[CH:41]=1

Participants

3

Reactant 2

HCID 178472108HCID 178472108, compoundHCID 178473544HCID 178473544, compound

Product 1

HCID 178473543HCID 178473543, compound

Procedure

The title compound was prepared following the procedure described in Example 160, replacing the compound of Example 159 with the compound of Example 165. The title compound was obtained as a white solid.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-942d5fd00c4a47818ce6d1c68454dee6
Source dataset
uspto-grants-2000_02
Patent number
US06028223

Reaction notes

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