HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 131721683, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 131721684 | HCID 131721684 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 131721683 | HCID 131721683 | 91% |
Reaction Steps
To the product from Example 178 (360 mg, 0.0005 mole) in H2O (8 mL) and CH3CN (8 mL) was added LiOH (88 mg, 0.0021 mole). The reaction was stirred at room temperature for 3 hours. The pH was lowered to ~3 with TFA and the product was isolated by RPHPLC to yield the title compound (300 mg after lyophilization) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06028223 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-e1d010b495934411bdf0541843413497 |
| Source note | uspto-grants-2000_02 |