HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 131721694, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 131721695 | HCID 131721695 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 131721694 | HCID 131721694 | 79.3% |
Reaction Steps
To the product from Example 188 (370 mg, 0.00057 mole) in H2O (20 mL) and CH3CN (15 mL) was added LiOH (192 mg, 0.0046 mole). The reaction mixture was stirred at room temperature for 3 hours. The pH was lowered to ~2.5 with TFA and the product was isolated by RPHPLC to yield the title compound (280 mg after lyophilization) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06028223 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-6471835b4f21417c95714d89e412df17 |
| Source note | uspto-grants-2000_02 |