Lithium Hydroxide → HCID 131721696, compound

Participants

Reaction Steps

To the product from Example 190 (200 mg, 0.00032 mole) in H2O (10 mL) and CH3CN (10 mL) was added LiOH (54 mg, 0.0013 mole). The reaction mixture was stirred at room temperature for 1.5 hours. The pH was lowered to ~2.5 with TFA and the product was isolated by RPHPLC to yield the title product (190 mg after lyophilization) as a white solid.

Provenance & Evidence