Ethanethiol → HCID 520033, compound

Participants

Reaction Steps

Thioethanol (5.0 g, 64 mmol), hexadecyl bromide (25.0 g, 82 mmol), and KOH (4.5 g, 80 mmol) were combined in 95% EtOH (150 mL). The reaction mixture was stirred at room temperature overnight and then diluted with H2O. The precipitate was collected and recrystallized from MeOH to provide the thioether: 19.0 g, 96%; mp 50° C.; NMR (300 MHz, CDCl3) δ 0.89 (t, 3 H, CH3), 1,30 (m, 26 H, (CH2)13), 1.60 (m, 2 H, CH2CH2S), 2.52 (t, 2 H, SCH2), 2.72 (m, 2 H, CH2S), 3.72 (m, 2 H, CH2OH).

Provenance & Evidence