Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trimethylsilylacetylene → (4-Isopropyl-phenylethynyl)-trimethyl-silane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trimethylsilylacetylene | HCID 66111 | — |
| 반응물 | p-Iodocumene | HCID 87073 | — |
| 촉매 | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| 촉매 | HCID 178418476 | HCID 178418476 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | (4-Isopropyl-phenylethynyl)-trimethyl-silane | HCID 23390603 | — |
반응 단계
To a solution of 4-iodoisopropylbenzene (12.3 g, 50 mmol, Lancaster Chemical Co.) in triethylamine (150 mL) was added trimethylsilylacetylene (5.89 g, 60 mmol), dichlorobis(triphenylphosphine)palladium(II) (0.70 g, 1 mmol, Aldrich), and copper(I) iodide (1.5 g). The reaction was stirred at room temperature for 18 hours, diluted with hexanes and filtered. The filtrate was evaporated under reduced pressure to give crude 1-(4-(2-propyl)phenyl)-2-trimethylsilyl acetylene.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06030969 |
| 출처 데이터셋 | uspto-grants-2000_02 |
| ORD ID | ord-bc724c04606843b5aea9cb9974912595 |
| 출처 메모 | uspto-grants-2000_02 |