HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 1-Methyl-1H-indole-6-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 1-Methyl-1H-indole-6-carbonitrile | HCID 15384493 | — |
| Reactant | Water ethanol | HCID 19096565 | — |
| Product | 1-Methyl-1H-indole-6-carboxylic acid | HCID 19819261 | — |
Reaction Steps
1-Methyl-6-cyanoindole (3.12 g, 21.9 mmole) was heated at reflux in 180 mL of ethanol/water (8:1) containing 15 g of potassium hydroxide to give 3.0 g of 1-methyl-1H-indole-6-carboxylic acid as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06030994 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-9e4a39983af24b9d8f92fdf75b76b2d8 |
| Source note | uspto-grants-2000_02 |