反应详情

A mixture of 1-chloro-4-nitro-benzene (10 g, 64 mmol) and ethane-1,2-diamine (38 mL) was heated at reflux for 4 h. Excess ethane-1,2-diamine was evaporated under reduced pressure and water was added to the residue. The precipitated solid was filtered off and dried under vacuum to afford N*1*-(4-nitro-phenyl)-ethane-1,2-diamine (10.8 g, quantitative).

1. temperaturewas heated
2. temperatureat reflux for 4 h
3. customExcess ethane-1,2-diamine was evaporated under reduced pressure and water
4. additionwas added to the residue
5. filtrationThe precipitated solid was filtered off
6. customdried under vacuum