4-(2-Chloroethyl)morpholine → HCID 19353967, compound

HRID 378405Notes

Reaction equation

HRID 378405 reaction equation
[F:1][C:2]([F:33])([F:32])[C:3]1[CH:31]=[CH:30][CH:29]=[CH:28][C:4]=1[CH2:5][N:6]1[C:10]2[CH:11]=[C:12]([OH:15])[CH:13]=[CH:14][C:9]=2[N:8]=[C:7]1[C:16]1[CH:21]=[C:20]([O:22][CH3:23])[C:19]([O:24][CH3:25])=[C:18]([O:26][CH3:27])[CH:17]=1.[N:34]1([CH2:40][CH2:41]Cl)[CH2:39][CH2:38][O:37][CH2:36][CH2:35]1>>[F:33][C:2]([F:1])([F:32])[C:3]1[CH:31]=[CH:30][CH:29]=[CH:28][C:4]=1[CH2:5][N:6]1[C:10]2[CH:11]=[C:12]([O:15][CH2:41][CH2:40][N:34]3[CH2:39][CH2:38][O:37][CH2:36][CH2:35]3)[CH:13]=[CH:14][C:9]=2[N:8]=[C:7]1[C:16]1[CH:17]=[C:18]([O:26][CH3:27])[C:19]([O:24][CH3:25])=[C:20]([O:22][CH3:23])[CH:21]=1

Participants

3

Reactant 2

HCID 767274-(2-Chloroethyl)morpholineHCID 15388688HCID 15388688, compound

Product 1

HCID 19353967HCID 19353967, compound

Procedure

The title compound was prepared by reacting the compound of Example 104 with 2-(morpholin-4-yl)ethyl chloride essentially as previously described. mp 175° C., NMR, IR, MS 572.

Sources & evidence

ORD record
ord-3c246fee11ca4235be31c59bb6c61fb8
Source dataset
uspto-grants-2000_02
Patent number
US06030992

Reaction notes

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