HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride, 2,5-dimethyl- → 2,5-Dimethyl-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride, 2,5-dimethyl- | HCID 87910 | — |
| Reactant | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| Product | 2,5-Dimethyl-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide | HCID 18617377 | 81% |
Reaction Steps
2,5-Dimethyl-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide was prepared from 5-amino-4-bromo-3-methylisoxazole and 2,5-dimethylbenzenesulfonyl chloride according to the procedures described in Example 25b. The crude product was purified by recrystallization from ethyl acetate/hexanes to give off-white crystals, m.p. 102-104° C., yield 81%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06030991 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-8f4a96a0d88949fab8321943bc4f42ee |
| Source note | uspto-grants-2000_02 |