HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4,5-Trichlorobenzenesulfonyl chloride → 2,4,5-Trichloro-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4,5-Trichlorobenzenesulfonyl chloride | HCID 27575 | — |
| Reactant | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| Product | 2,4,5-Trichloro-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide | HCID 18617286 | 67% |
Reaction Steps
2,4,5-Trichloro-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide was prepared from 5-amino-4-bromo-3-methylisoxazole and 2,4,5-trichlorobenzenesulfonyl chloride according to the procedures described in Example 30. The crude product was purified by recrystallization from ethyl acetate/hexanes to give a crystalline solid, m.p. 179-182° C., yield 67%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06030991 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-3e3c6d3cebdb48c893139c026fd35837 |
| Source note | uspto-grants-2000_02 |