反应详情

温度

90 °C

A mixture of 8.91 g (135 mmol) 85% aqueous KOH solution and 20 ml water is added to 16.3 g (38.57 mmol) 2,5-dihexoxyterephthalic acid diethyl ester in 20 ml ethanol and the whole is stirred for 2 hours at 90° C. The crude product precipitated by the dropwise addition of 12.5 ml conc. HCl with ice-cooling is filtered off, washed neutral with water and recrystallized from ethanol.

1. customThe crude product precipitated by the dropwise addition of 12.5 ml conc. HCl with ice-
2. temperaturecooling
3. filtrationis filtered off
4. washwashed neutral with water
5. customrecrystallized from ethanol