Benzoyl Peroxide → HCID 22006937, compound

HRID 378513Notes

Reaction equation

HRID 378513 reaction equation
[CH3:1][N:2]1[C:6](=[O:7])[N:5]([C:8]2[CH:13]=[CH:12][C:11]([CH3:14])=[CH:10][CH:9]=2)[CH:4]=[N:3]1.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1.[Br:33]N1C(=O)CCC1=O>C(Cl)(Cl)(Cl)Cl>[CH3:1][N:2]1[C:6](=[O:7])[N:5]([C:8]2[CH:13]=[CH:12][C:11]([CH2:14][Br:33])=[CH:10][CH:9]=2)[CH:4]=[N:3]1

Participants

5

Reactant 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 22006946HCID 22006946, compound

Product 1

HCID 22006937HCID 22006937, compoundYield 74.6%

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

To a stirred solution of 2.6 grams (0.013 mole) of 4,5-dihydro-1-methyl-5-oxo-4-(4-methylphenyl)-1H-1,2,4-triazole in 150 mL of carbon tetrachloride were added 0.3 gram (catalyst) of benzoyl peroxide and 2.5 grams (0.014 mole) of N-bromosuccinimide. The reaction mixture was heated at reflux for three hours, after which it was cooled and concentrated under reduced pressure, yielding 2.6 grams of 4,5-dihydro-1-methyl-5-oxo4-(4-bromomethylphenyl)-1H-1,2,4-triazole, which was used in the next reaction without further characterization.

Workup

  1. temperatureThe reaction mixture was heated
  2. temperatureat reflux for three hours
  3. temperatureafter which it was cooled
  4. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-60989c3bef1f4ec694956d190ac7085c
Source dataset
uspto-grants-2000_02
Patent number
US06030987

Reaction notes

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