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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 378606Generated: October 30, 2026

Benzoyl chloride → HCID 18349809, compound

https://huagongshe.com/reaction/378606

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl chlorideHCID 7412—
ReactantHCID 18349546HCID 18349546—
SolventDichloromethaneHCID 6344—
ProductHCID 18349809HCID 18349809—

Reaction Conditions

Temperature0 °C

Reaction Steps

A solution of benzoyl chloride (0.2 g) in dichloromethane (3 ml) was added dropwise to a solution of N-{1-[4-(2-aminoethyl)phenyl]-1-methylethyl}-3-(imidazol-1-yl)propylamine (0.4 g) in dichloromethane (7 ml) with stirring at 0° C. The mixture was treated in a similar manner to Example 55 to give N-[2-(4-{1-[3-(imidazol-1-yl)propylamino]-1-methylethyl}phenyl)ethyl]benzamide as an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06031109
Source datasetuspto-grants-2000_02
ORD IDord-ffe6ac99728f4fcabadea770d0ff1d8a
Source noteuspto-grants-2000_02