N-(1,1-dimethyl-2-phenoxyethyl)acrylamide → 3-[4-(2-Aminoethyl)imidazol-1-yl]-N-(1,1-dimethyl-2-phenoxyethyl)propylamin

HRID 378649Notes

Reaction equation

HRID 378649 reaction equation
[CH3:1][C:2]([NH:12][C:13](=O)[CH:14]=[CH2:15])([CH3:11])[CH2:3][O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[C:17]([CH2:19][C:20]1[N:21]=[CH:22][NH:23][CH:24]=1)#[N:18]>>[NH2:18][CH2:17][CH2:19][C:20]1[N:21]=[CH:22][N:23]([CH2:15][CH2:14][CH2:13][NH:12][C:2]([CH3:11])([CH3:1])[CH2:3][O:4][C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:24]=1

Participants

3

Reactant 2

HCID 18349576N-(1,1-dimethyl-2-phenoxyethyl)acrylamideHCID 178510863HCID 178510863, compound

Product 1

HCID 183498003-[4-(2-Aminoethyl)imidazol-1-yl]-N-(1,1-dimethyl-2-phenoxyethyl)propylamin

Procedure

The title compound was prepared in a similar manner to the Example immediately above from N-(1,1-dimethyl-2-phenoxyethyl)acrylamide and 4-cyanomethyl-imidazole.

Sources & evidence

ORD record
ord-741b8ab6416d4ab8ae0c365cc99c9048
Source dataset
uspto-grants-2000_02
Patent number
US06031109

Reaction notes

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