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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 378669Generated: October 31, 2026

Acetaldehyde → (RS)-8-(4-Benzyloxy-phenyl)-2-(1-hydroxy-ethyl)-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid (2-methoxy-ethyl)-phenyl-amide

https://huagongshe.com/reaction/378669

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetaldehydeHCID 177—
Reactant8-(4-Benzyloxy-phenyl)-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid (2-methoxy-ethyl)-phenyl-amideHCID 56636258—
Product(RS)-8-(4-Benzyloxy-phenyl)-2-(1-hydroxy-ethyl)-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid (2-methoxy-ethyl)-phenyl-amideHCID 56609835—

Reaction Steps

By lithiation of 8-(4-benzyloxy-phenyl)-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid (2-methoxy-ethyl)-phenyl-amide and reaction with acetaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06030984
Source datasetuspto-grants-2000_02
ORD IDord-66076619984845d7b0ca1ac35f5e20b9
Source noteuspto-grants-2000_02