反应详情

At −10° C., 100 g (0.48 mol) of 3-[(2,5-dimethylphenyl)thio]propanoic acid were dissolved in 2200 ml of conc. sulfuric acid. The reaction solution was stirred at room temperature for 1 h and then poured onto crushed ice. The aqueous solution was extracted with a diethyl ether/hexane mixture (1:9) (6×500 ml). The combined organic phases were dried over MgSO4 and concentrated completely using a rotary evaporator.

1. additionpoured
2. customonto crushed ice
3. extractionThe aqueous solution was extracted with a diethyl ether/hexane mixture (1:9) (6×500 ml)
4. dry with materialThe combined organic phases were dried over MgSO4
5. concentrationconcentrated completely
6. customa rotary evaporator