Hydrochloric Acid → HCID 70204619, compound

Participants

Reaction Steps

1.0 g (4.1 mmol) of 5,8-dimethyl-4-hydroxy-1,1-dioxo-1,2,3,4-tetrahydro-1λ6-thiochromene-6-carboxylic acid, 0.58 g (4.1 mmol) of benzoyl chloride and a spatula tip of N,N-4-dimethylaminopyridine was stirred in 10 ml of pyridine overnight. The mixture was subsequently poured onto 5 M HCl in crushed ice and extracted with ethyl acetate. The organic phase was washed with 1 M HCl (2×20 ml) and sat. NaCl solution (2×40 ml), dried over MgSO4 and concentrated using a rotary evaporator.

Provenance & Evidence