反应详情

温度

90 °C

45.0 g (302.1 mmol) of 4,6-dichloropyrimidine are initially charged in 450 ml of water. 26.3 g (302.1 mmol) of morpholine are added, and the mixture is stirred at 90° C. for 16 h. The mixture is then cooled to 0° C., and the precipitate formed is filtered off. The precipitate is washed once with 50 ml of water and air-dried.

1. temperatureThe mixture is then cooled to 0° C.
2. customthe precipitate formed
3. filtrationis filtered off
4. washThe precipitate is washed once with 50 ml of water
5. customair-dried