Ethyl 4-amino-phenyloxyacetate hydrochloride → HCID 178473010, compound

HRID 378994Notes

Reaction equation

HRID 378994 reaction equation
[NH:1]([C:5]1[S:6][CH:7]=[C:8]([C:10]([OH:12])=O)[N:9]=1)[C:2]([NH2:4])=[NH:3].Cl.[NH2:14][C:15]1[CH:20]=[CH:19][C:18]([O:21][CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])=[CH:17][CH:16]=1>>[NH:1]([C:5]1[S:6][CH:7]=[C:8]([C:10]([NH:14][C:15]2[CH:16]=[CH:17][C:18]([O:21][CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])=[CH:19][CH:20]=2)=[O:12])[N:9]=1)[C:2]([NH2:4])=[NH:3]

Participants

3

Reactant 2

HCID 21697723Ethyl 4-amino-phenyloxyacetate hydrochlorideHCID 178512693HCID 178512693, compound

Product 1

HCID 178473010HCID 178473010, compound

Procedure

In the same manner as described in Example 3, from 2-guanidino-thiazole-4-carboxylic acid and ethyl 4-amino-phenyloxyacetate hydrochloride there is obtained ethyl {4-[(2-guanidino-thiazole-4-carbonyl)-amino]-phenoxy}-acetate, m.p. 206° C., MS: 364 (M+H)+.

Sources & evidence

ORD record
ord-ad020ac68e7148c48a9d2bae5319fc7e
Source dataset
uspto-grants-2001_10
Patent number
US06297266B1

Reaction notes

Loading…