Ethanol → HCID 131722875, compound

Participants

Reaction Steps

In a 100 ml round bottom flask equipped with an argon line was placed Nu-Phe-HPhe-CH2-Br (300 mg, 0.582 mmol), potassium fluoride (150 mg, 2.4 mmol), and potassium carbonate (150 mg, 1.2 mmol), and 8 ml of 200 proof ethanol. The reaction was stirred 3 hours, filtered and the solvents were removed under vacuum and the residue chromatographed on a short silica gel column (CHCl3:MLEOH 95:5) and then recrystallized from ether.

Provenance & Evidence