HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Proline → HCID 20691580, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Proline | HCID 145742 | — |
| Reactant | Methyl 10-oxoundecanoate | HCID 519622 | — |
| Reactant | 3-Pyridinecarboxaldehyde, 2-amino- | HCID 737633 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 20691580 | HCID 20691580 | — |
Reaction Steps
A mixture of 13-2 (9.2 g, 43 mmol), 1-3 (5.3 g, 43 mmol), proline (2.5 g, 22 mmol), and ethanol (215 mL) was heated to reflux for 20 h. The cooled reaction mixture was concentrated and the residue purified by flash chromatography (silica, EtOAc) to give 13-3 as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06297249B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-30ae78dbc64b4100aa4e2897a7331601 |
| Source note | uspto-grants-2001_10 |