HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluidine → 4-Aminobenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-amino-N-hydroxyphthalimide | HCID 10888472 | — |
| Product | 4-Aminobenzaldehyde | HCID 11158 | 62% |
Reaction Steps
172 mg (1.60 mmol) of 4-toluidine were reacted analogously to Example 1 in the presence of 32.1 mg (0.180 mmol) of 3-amino-N-hydroxyphthalimide. After a reaction time of 22 hours, the reaction solution was brought to pH 8 with 2M NaOH, extracted with chloroform and examined by NMR spectroscopy. Yield 62% of 4-aminobenzaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06297403B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-88309852da3943ec8314dc8d6a8b2fe7 |
| Source note | uspto-grants-2001_10 |