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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 379450Generated: October 30, 2026

4-(1-(4-fluorobenzyl)-1H-benzimidazole-2-carbonyl)piperidine → N-Methyl-N-(4-(4-(1-(4-fluorobenzyl)-1H-benzimidazole-2-carbonyl)piperidin-1-yl)-2-(3,4-dimethoxyphenyl)butyl)benzamide

https://huagongshe.com/reaction/379450

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(1-(4-fluorobenzyl)-1H-benzimidazole-2-carbonyl)piperidineHCID 15542883—
ReactantN-methyl-N-(2-(3,4-dimethoxyphenyl)-4-methanesulfonylbutyl)benzamideHCID 18354489—
ProductN-Methyl-N-(4-(4-(1-(4-fluorobenzyl)-1H-benzimidazole-2-carbonyl)piperidin-1-yl)-2-(3,4-dimethoxyphenyl)butyl)benzamideHCID 10168612—

Reaction Steps

Prepare by the method of Example 1.7 using N-methyl-N-(2-(3,4-dimethoxyphenyl)-4-methanesulfonylbutyl)benzamide and 4-(1-(4-fluorobenzyl)-1H-benzimidazole-2-carbonyl)piperidine to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06297259B1
Source datasetuspto-grants-2001_10
ORD IDord-feef688704a84ce1a812f58cc45a3db8
Source noteuspto-grants-2001_10