HCID 21697605, compound → HCID 10123112, compound

HRID 379452Notes

Reaction equation

[CH3:1][N:2]([CH2:17][CH:18]([C:25]1[CH:30]=[CH:29][CH:28]=[C:27]([C:31]([F:34])([F:33])[F:32])[CH:26]=1)[CH2:19][CH2:20]S(C)(=O)=O)[C:3](=[O:16])[C:4]1[CH:9]=[C:8]([O:10][CH3:11])[C:7]([O:12][CH3:13])=[C:6]([O:14][CH3:15])[CH:5]=1.I.[N:36]1[CH:41]=[CH:40][CH:39]=[CH:38][C:37]=1[CH2:42][N:43]1[C:47]2[CH:48]=[CH:49][CH:50]=[CH:51][C:46]=2[N:45]=[C:44]1[C:52]([CH:54]1[CH2:59][CH2:58][NH:57][CH2:56][CH2:55]1)=[O:53]>>[CH3:1][N:2]([CH2:17][CH:18]([C:25]1[CH:30]=[CH:29][CH:28]=[C:27]([C:31]([F:34])([F:33])[F:32])[CH:26]=1)[CH2:19][CH2:20][N:57]1[CH2:58][CH2:59][CH:54]([C:52]([C:44]2[N:43]([CH2:42][C:37]3[CH:38]=[CH:39][CH:40]=[CH:41][N:36]=3)[C:47]3[CH:48]=[CH:49][CH:50]=[CH:51][C:46]=3[N:45]=2)=[O:53])[CH2:55][CH2:56]1)[C:3](=[O:16])[C:4]1[CH:9]=[C:8]([O:10][CH3:11])[C:7]([O:12][CH3:13])=[C:6]([O:14][CH3:15])[CH:5]=1

Participants

Reactant 2

HCID 21697605HCID 21697605, compound

HCID 86754909HCID 86754909, compound

Product 1

HCID 10123112HCID 10123112, compound

Procedure

Prepare by the method of Example 1.7 using N-methyl-N-(2-(3-trifluoromethylphenyl)-4-methanesulfonylbutyl)-3,4,5-trimethoxybenzamide and 4-(1-(pyrid-2-ylmethyl)-1H-benzimidazole-2-carbonyl)piperidine hydriodic acid salt to give the title compound.

Sources & evidence

ORD record: ord-b3a44b5de77243f8b6a000b3ab6d5ae3
Source dataset: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06297259B1

Reaction notes

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