Ethane, 1-chloro-2-ethoxy- → HCID 21697433, compound

HRID 379469Notes

Reaction equation

HRID 379469 reaction equation
[CH3:1][N:2]([CH2:17][CH:18]([C:38]1[CH:43]=[CH:42][CH:41]=[C:40]([Cl:44])[CH:39]=1)[CH2:19][CH2:20][N:21]1[CH2:26][CH2:25][CH:24]([C:27]([C:29]2[NH:33][C:32]3[CH:34]=[CH:35][CH:36]=[CH:37][C:31]=3[N:30]=2)=[O:28])[CH2:23][CH2:22]1)[C:3](=[O:16])[C:4]1[CH:9]=[C:8]([O:10][CH3:11])[C:7]([O:12][CH3:13])=[C:6]([O:14][CH3:15])[CH:5]=1.[CH2:45]([O:47][CH2:48][CH2:49]Cl)[CH3:46]>>[CH3:1][N:2]([CH2:17][CH:18]([C:38]1[CH:43]=[CH:42][CH:41]=[C:40]([Cl:44])[CH:39]=1)[CH2:19][CH2:20][N:21]1[CH2:26][CH2:25][CH:24]([C:27]([C:29]2[N:30]([CH2:46][CH2:45][O:47][CH2:48][CH3:49])[C:31]3[CH:37]=[CH:36][CH:35]=[CH:34][C:32]=3[N:33]=2)=[O:28])[CH2:23][CH2:22]1)[C:3](=[O:16])[C:4]1[CH:9]=[C:8]([O:10][CH3:11])[C:7]([O:12][CH3:13])=[C:6]([O:14][CH3:15])[CH:5]=1

Participants

3

Reactant 2

HCID 12341Ethane, 1-chloro-2-ethoxy-HCID 21697381HCID 21697381, compound

Product 1

HCID 21697433HCID 21697433, compound

Procedure

Prepare by the method of Example 21.1 using N-methyl-N-(4-(4-(1H-benzimidazole-2-carbonyl)piperidin-1-yl)-2-(3-chlorophenyl)butyl)-3,4,5-trimethoxybenzamide and 2-chloroethyl ethyl ether to give the title compound.

Sources & evidence

ORD record
ord-4c76ed9c5ca34f1aa4bed9606481160e
Source dataset
uspto-grants-2001_10
Patent number
US06297259B1

Reaction notes

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