HCID 18333276, compound → HCID 21697516, compound

HRID 379470Notes

Reaction equation

HRID 379470 reaction equation
[CH3:1][N:2]([CH2:17][CH:18]([C:25]1[CH:30]=[CH:29][C:28]([Cl:31])=[CH:27][CH:26]=1)[CH2:19][CH2:20]S(C)(=O)=O)[C:3](=[O:16])[C:4]1[CH:9]=[C:8]([O:10][CH3:11])[C:7]([O:12][CH3:13])=[C:6]([O:14][CH3:15])[CH:5]=1.I.[NH:33]1[C:37]2[CH:38]=[CH:39][CH:40]=[CH:41][C:36]=2[N:35]=[C:34]1[C:42]([CH:44]1[CH2:49][CH2:48][NH:47][CH2:46][CH2:45]1)=[O:43]>>[CH3:1][N:2]([CH2:17][CH:18]([C:25]1[CH:30]=[CH:29][C:28]([Cl:31])=[CH:27][CH:26]=1)[CH2:19][CH2:20][N:47]1[CH2:48][CH2:49][CH:44]([C:42]([C:34]2[NH:33][C:37]3[CH:38]=[CH:39][CH:40]=[CH:41][C:36]=3[N:35]=2)=[O:43])[CH2:45][CH2:46]1)[C:3](=[O:16])[C:4]1[CH:9]=[C:8]([O:10][CH3:11])[C:7]([O:12][CH3:13])=[C:6]([O:14][CH3:15])[CH:5]=1

Participants

3

Reactant 2

HCID 18333276HCID 18333276, compoundHCID 18354443N-methyl-N-(2-(4-chlorophenyl)-4-methanesulfonylbutyl)-3,4,5-trimethoxybenzamide

Product 1

HCID 21697516HCID 21697516, compound

Procedure

Prepare by the method of Example 1.7 using N-methyl-N-(2-(4-chlorophenyl)-4-methanesulfonylbutyl)-3,4,5-trimethoxybenzamide and 4-(1H-benzimidazole-2-carbonyl)piperidine hydriodic acid salt to give the title compound.

Sources & evidence

ORD record
ord-876930ea83cb4edda3ebff6c5ed6e4ed
Source dataset
uspto-grants-2001_10
Patent number
US06297259B1

Reaction notes

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