Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Lactide | HCID 7272 | — |
| Reactant | 1-Decanol | HCID 8174 | — |
| Reactant | 2-ethylhexanoic acid tin(II) salt | HCID 9318 | — |
| Reactant | epsilon-CAPROLACTONE | HCID 10401 | — |
| Reactant | Glycolide | HCID 65432 | — |
| Product | Poliglecaprone | HCID 65431 | — |
Reaction Steps
Glycolide (0.13 moles) was mixed with ε-caprolactone (1.18) and a catalytic amount of stannous octoate (0.262 mole) and 1-decanol (3.275 mole). The system was heated to 170° C. and was stirred at this temperature for 30 minutes. The reaction was then cooled to 120° C. Glycolide (0.65 moles) and dl-lactide (0.52 moles) were added to the prepolymer. After melting the second charge, the system was heated to 170° C. and was stirred at this temperature for 6.5 hours. At the conclusion of the reaction, the unreacted monomer was removed by heating at 130° C. under reduced pressure for 1.5 hours. The resulting polymer was characterized by DSC (for Tm), solution viscosity (for molecular dimensions), IR and NMR (for chemical composition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06299631B1 |
|---|
| Source dataset | uspto-grants-2001_10 |
|---|
| ORD ID | ord-1c558c26d9dd4b188c9a0b7c258b08d4 |
|---|
| Source note | uspto-grants-2001_10 |
|---|
