HCID 18320642, compound → HCID 15433019, compound
Reaction equation
[Cl:1][CH2:2][CH2:3][N:4]1[C:8]([CH3:10])([CH3:9])[C:7]2[CH:11]=[CH:12][C:13]([N+]([O-])=O)=[CH:14][C:6]=2[S:5]1(=[O:19])=[O:18].ClCCN1C(CC)(CC)C2C=CC=CC=2S1(=O)=O.ClCCN1C(C)(C)C2C(Cl)=CC=CC=2S1(=O)=O>>[Cl:1][CH2:2][CH2:3][N:4]1[C:8]([CH3:10])([CH3:9])[C:7]2[CH:11]=[CH:12][CH:13]=[CH:14][C:6]=2[S:5]1(=[O:19])=[O:18]Participants
4
Procedure
2-(2-Chloroethyl)-3,3-dimethyl-6-nitro-2,3-dihydro-1, 2-benzoisothiazole 1,1-dioxide, 2-(2-chloroethyl)-3, 3-diethyl-2,3-dihydro-1,2-benzoisothiazole 1,1-dioxide and 2-(2-chloroethyl)-4-chloro-3,3-dimethyl-2,3-dihydro-1, 2-benzoisothiazole 1,1-dioxide can be prepared in an analogous manner.
Sources & evidence
- ORD record
- ord-b8e326fb8a71415ea6dbd3e8db92f6a1
- Source dataset
- uspto-grants-2001_10
- Patent number
- US06300354B1
Reaction notes
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