Ethyl iodoacetate → HCID 69952028, compound

HRID 379677Notes

Reaction equation

[C:1]1([CH2:11][NH:12][C:13]2[CH:14]=[C:15]3[C:20](=[CH:21][CH:22]=2)[N:19]([C:23](=[O:34])[CH2:24][CH2:25][C:26]2[CH:31]=[CH:30][C:29]([C:32]#[N:33])=[CH:28][CH:27]=2)[CH2:18][CH2:17][CH2:16]3)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.I[CH2:36][C:37]([O:39][CH2:40][CH3:41])=[O:38]>>[CH2:40]([O:39][C:37]([CH2:36][N:12]([CH2:11][C:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1)[C:13]1[CH:14]=[C:15]2[C:20](=[CH:21][CH:22]=1)[N:19]([C:23](=[O:34])[CH2:24][CH2:25][C:26]1[CH:31]=[CH:30][C:29]([C:32]#[N:33])=[CH:28][CH:27]=1)[CH2:18][CH2:17][CH2:16]2)=[O:38])[CH3:41]

Participants

Reactant 2

HCID 12183Ethyl iodoacetate

HCID 18366939HCID 18366939, compound

Product 1

HCID 69952028HCID 69952028, compound

Procedure

Prepared from 6-[(naphthalin-1-ylmethyl)-amino]-1-[3-(4-cyano-phenyl)-propionyl]-1,2,3,4-tetrahydro-quinoline (see Example 14(1)) and ethyl iodoacetate

Sources & evidence

ORD record: ord-d232498852254636a23713a378da8d65
Source dataset: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06300342B1

Reaction notes

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