Ethanol → HCID 9909404, compound

HRID 379701Notes

Reaction equation

HRID 379701 reaction equation
[CH2:1]([N:3]([CH2:26][CH3:27])[CH2:4][CH2:5][O:6][C:7]1[CH:25]=[CH:24][C:10]([NH:11][C:12](=[O:23])[C:13]2[C:18]([O:19][CH3:20])=[CH:17][CH:16]=[CH:15][C:14]=2[O:21][CH3:22])=[CH:9][CH:8]=1)[CH3:2].C(O)C.[ClH:31].C(O)C>C(OCC)C>[ClH:31].[CH2:26]([N:3]([CH2:1][CH3:2])[CH2:4][CH2:5][O:6][C:7]1[CH:25]=[CH:24][C:10]([NH:11][C:12](=[O:23])[C:13]2[C:14]([O:21][CH3:22])=[CH:15][CH:16]=[CH:17][C:18]=2[O:19][CH3:20])=[CH:9][CH:8]=1)[CH3:27]

Participants

5

Reactant 3

HCID 702EthanolHCID 9909405HCID 9909405, compoundHCID 21887872Ethanol hydrochloride

Product 1

HCID 9909404HCID 9909404, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

4′-[2-(Diethylamino)ethoxy]-2,6-dimethoxybenzanilide (2.17 g) was dissolved into ethanol (20 ml) and added with 1N HCl/ethanol (12 ml) and then stirred. The reaction mixture was added with ethyl ether (100 ml) and insolubles precipitated were collected by filtration and dried under vacuum to obtain 4′-[2-(diethylamino)ethoxy]-2,6-dimethoxybenzanilide hydrochloride (2.29 g) as color-less crystal.

Workup

  1. customprecipitated
  2. filtrationwere collected by filtration
  3. customdried under vacuum

Sources & evidence

ORD record
ord-2e51061472794430a706134fc4fe335f
Source dataset
uspto-grants-2001_10
Patent number
US06300368B1

Reaction notes

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