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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 379754Generated: October 26, 2026

2-Bromo-1-[4-(trifluoromethoxy)phenyl]ethan-1-one → 3-Amino-6-chloro-1-ethoxycarbonyl-2-(4-trifluoromethoxybenzoyl)indole

https://huagongshe.com/reaction/379754

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-1-[4-(trifluoromethoxy)phenyl]ethan-1-oneHCID 2778691—
Reactant4-Chloro-2-[(ethoxycarbonyl)amino]benzonitrileHCID 18367888—
Product3-Amino-6-chloro-1-ethoxycarbonyl-2-(4-trifluoromethoxybenzoyl)indoleHCID 18368133—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 1 from 4-chloro-2-(ethoxycarbonylamino)benzonitrile (Example 1, step 1) and 2-bromo-4′-trifluoromethoxyacetophenone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06300363B1
Source datasetuspto-grants-2001_10
ORD IDord-9f890b9f50f9467993c61a597e57d9ee
Source noteuspto-grants-2001_10