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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 379755Generated: October 31, 2026

2-Bromo-1-(4-chloro-3-methylphenyl)ethanone → 3-Amino-6-chloro-2-(4-chloro-3-methylbenzoyl)-1-(ethoxycarbonyl)indole

https://huagongshe.com/reaction/379755

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-1-(4-chloro-3-methylphenyl)ethanoneHCID 592802—
Reactant4-Chloro-2-[(ethoxycarbonyl)amino]benzonitrileHCID 18367888—
Product3-Amino-6-chloro-2-(4-chloro-3-methylbenzoyl)-1-(ethoxycarbonyl)indoleHCID 18368095—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 1 from 4-chloro-2-(ethoxycarbonylamino)benzonitrile (Example 1, step 1) and 2-bromo-4′-chloro-3′-methylacetophenone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06300363B1
Source datasetuspto-grants-2001_10
ORD IDord-99457f7e95fc48bcbf9d9fe9133e9c52
Source noteuspto-grants-2001_10