HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1-(thiophen-2-yl)ethan-1-one → 3-Amino-6-chloro-1-(ethoxycarbonyl)-2-(thiophene-2-carbonyl)indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1-(thiophen-2-yl)ethan-1-one | HCID 2776372 | — |
| Reactant | 4-Chloro-2-[(ethoxycarbonyl)amino]benzonitrile | HCID 18367888 | — |
| Product | 3-Amino-6-chloro-1-(ethoxycarbonyl)-2-(thiophene-2-carbonyl)indole | HCID 18368089 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step 2 of Example 1 from 4-chloro-2-(ethoxycarbonylamino)benzonitrile (Example 1, step 1) and 2-(bromoacetyl)thiophene (Steinkopt, Justus Liebig Ann. Chem., 1923, 430, 103).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06300363B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-d93faaded64c421da127d555d7bcbf6e |
| Source note | uspto-grants-2001_10 |