4-(Bromoacetyl)pyridine hydrobromide → HCID 18367794, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 1 from 4-chloro-2-(ethoxycarbonylamino)benzonitrile (Example 1, step 1) and 4-(bromoacetyl)pyridine hydrobromide (A. Taurins and A. Blage, J. Heterocycl. Chem., 1970, 7, 1137-1141). 1H-NMR (CDCl3) δ: 8.75-8.73 (2H, m), 8.24 (1H, d, J=1.5 Hz), 7.57-7.54 (3H, m), 7.33 (1H, dd, J=1.8, 8.4 Hz), 6.04 (2H, br s), 3.82 (2H, q, J=7.0 Hz), 0.93 (3H, t, J=7.0 Hz)

Provenance & Evidence