HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-[(ethoxycarbonyl)amino]benzonitrile → 3-Amino-6-chloro-2-(4-chloropyridine-2-carbonyl)-1-(ethoxycarbonyl)indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-[(ethoxycarbonyl)amino]benzonitrile | HCID 18367888 | — |
| Reactant | 2-Bromo-1-(4-chloro-pyridin-2-yl)-ethanone hydrobromide | HCID 23003349 | — |
| Product | 3-Amino-6-chloro-2-(4-chloropyridine-2-carbonyl)-1-(ethoxycarbonyl)indole | HCID 18368177 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step 2 of Example 1 from 4-chloro-2-(ethoxycarbonylamino)benzonitrile (Example 1, step 1) and 2-(bromoacetyl)-4-chloropyridine hydrobromide*.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06300363B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-aed876fa6a2d4ad19ab6487869e7955e |
| Source note | uspto-grants-2001_10 |