Acetone → HCID 18367881, compound

HRID 379779Notes

Reaction equation

HRID 379779 reaction equation
[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[N:4]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[C:3]=1[C:17]([C:19]1[CH:24]=[N:23][CH:22]=[CH:21][N:20]=1)=[O:18].[CH3:25][C:26](C)=[O:27]>>[C:26]([NH:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[N:4]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[C:3]=1[C:17]([C:19]1[CH:24]=[N:23][CH:22]=[CH:21][N:20]=1)=[O:18])(=[O:27])[CH3:25]

Participants

3

Reactant 2

HCID 180AcetoneHCID 183681103-Amino-6-chloro-1-(ethoxycarbonyl)-2-(pyrazine-2-carbonyl)indole

Product 1

HCID 18367881HCID 18367881, compound

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 2 (Method A) from 3-amino-6-chloro-1-(ethoxycarbonyl)-2-(pyrazine-2-carbonyl)indole (step 1). tlc: Rf=0.4 (50% acetone in hexanes)

Sources & evidence

ORD record
ord-8e78ed07a5a04f168c0c0ab00647d3ef
Source dataset
uspto-grants-2001_10
Patent number
US06300363B1

Reaction notes

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