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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 379794Generated: October 25, 2026

Phenacyl bromide → 3-Amino-2-benzoyl-5-chloro-1-(ethoxycarbonyl)indole

https://huagongshe.com/reaction/379794

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenacyl bromideHCID 6259—
ReactantEthyl 4-chloro-2-cyanophenylcarbamateHCID 21779762—
Product3-Amino-2-benzoyl-5-chloro-1-(ethoxycarbonyl)indoleHCID 18368001—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 1 from 5-chloro-2-(ethoxycarbonylamino)benzonitrile (K. O. Geolotte et al, J. Heterocyclic Chem., 1990, 27, 1549) and 2-bromoacetophenone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06300363B1
Source datasetuspto-grants-2001_10
ORD IDord-c0c77cd4b9e9480fa2605c1771660c07
Source noteuspto-grants-2001_10